This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie COFUND grant agreement No 665735.

General Information.
The Nencki Institute of Experimental Biology (http://en.nencki.gov.pl/) of the Polish Academy of Sciences (PAS), founded in 1918, is the first and one of the largest (345 staff including 115 researchers and over 130 PhD students) non-university institutions in Poland in the field of biology. It is a basic research institute, state owned. Neurobiology, Biochemistry and Cell Biology are its focal areas. High quality of externally funded research (over 60 projects running, of which over 20 are international – NIH, EMBO, Wellcome Trust, NATO, EU FP6 and 7) and excellent publication record (well over 100 peerreviewed publications on the ISI list and over 2000 citations annually, 10 of 35 Polish most-cited biologists) place the Institute among the leading biological institutions in Central Europe. The Nencki Institute was awarded the status of the Centre of Excellence for Studies on Neurodegeneration (supported by PHARE Sci-Tech II grant) and the EU Centre of Excellence in Neurobiology (supported by an FP5-funded project BRAINS). In 2013 the European Commission has awarded the Institute, as the first research unit in Poland, the prestigious HR Excellence in Research badge.

Key Research facilities and infrastructure.
Nencki Institute’s infrastructure includes state of the art units and core laboratories of confocal microscopy, electron and atomic force microscopy, Viral Vectors and Transgenisation of Rodents, Behavioural Tests (full battery of tests from emotion to addiction), modern Animal House and surgery facilities, 3T fMRI scanner for humans, fully equipped cell and molecular biology facilities including tissue culture, as well as bioinformatics team to assist scientists in data analyses (genomics, imaging).

Scientific and training environment.
The Nencki Institute hosts 41 PIs including the most highly cited biology researchers in Poland. The major asset of Nencki is the vast expertise of its researchers in studies at all major levels of nature organization, namely molecular, sub-cellular, cellular as well as at the whole organism and behaviour level (systems level) which can be applied to understand animal and human physiology and pathology. In particular, recent efforts at the Institute’s transgenic facility, which is unique in Poland, successfully produced transgenic rats and mice expressing specific fluorescent protein reporters in the brain. These models allow developing novel tools for imagining function from molecules to the whole organism. Visualization of the protein-protein interactions in vitro and vivo, sub-cellular organelle dynamics, cellular function and dysfunction and finally imaging of the organs all require novel experimental approaches. With very rapid technological progress in healthcare industry, being an important bio-medical centre required recruitment of top-notch experienced researchers as a young group leaders and intensifying close collaborations with European centres of excellence in this field of study. Over the last ten years the number of young group leaders in bio-medical research fields at the Nencki Institute significantly increased.

For more information see: http://en.nencki.gov.pl/